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Isil Keskin
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isil.keskin@umu.se
Verksam som
Anknytning
Forskare vid
Institutionen för klinisk vetenskap
Enhet: Neurovetenskaper
Plats
Norrlands universitetssjukhus, Umeå universitet, Klinisk vetenskap
Umeå universitet, Klinisk vetenskap, 901 85 Umeå
Anknytning
Institutionen för medicinsk biovetenskap
Enhet: Patologi
Plats
By 6M, Sjukhusområdet
Umeå universitet, 901 85 Umeå
Publikationer
Publikationer
Forskning
Forskning
2025
A comparison of p-tau assays for the specificity to detect tau changes in Alzheimer's disease
Alzheimer's & Dementia: Journal of the Alzheimer's Association
, John Wiley & Sons 2025, Vol. 21, (4)
Janelidze, Shorena; Ashton, Nicholas J.; Orduña Dolado, Anna; et al.
2023
The motor system is exceptionally vulnerable to absence of the ubiquitously expressed superoxide dismutase-1
Brain Communications
, Oxford University Press 2023, Vol. 5, (1)
Park, Julien H.; Nordström, Ulrika; Tsiakas, Konstantinos; et al.
2021
Peripheral administration of SOD1 aggregates does not transmit pathogenic aggregation to the CNS of SOD1 transgenic mice
Acta neuropathologica communications
, BioMed Central 2021, Vol. 9, (1)
Keskin, Isil; Ekhtiari Bidhendi, Elaheh; Marklund, Matthew; et al.
2019
The molecular pathogenesis of superoxide dismutase 1-linked ALS is promoted by low oxygen tension
Acta Neuropathologica
, New York: Springer 2019, Vol. 138, (1) : 85-101
Keskin, Isil; Forsgren, Elin; Lehmann, Manuela; et al.
2017
Comprehensive analysis to explain reduced or increased SOD1 enzymatic activity in ALS patients and their relatives
Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration
, TAYLOR & FRANCIS LTD 2017, Vol. 18, (5-6) : 457-463
Keskin, Isil; Birve, Anna; Berdynski, Mariusz; et al.
2016
SOD, ORF and ALS: On the role of
SOD1
and
C9ORF72
in the pathogenesis of ALS
Umeå University medical dissertations
, 1829
Keskin, Isil
2016
Effects of Cellular Pathway Disturbances on Misfolded Superoxide Dismutase-1 in Fibroblasts Derived from ALS Patients
PLOS ONE
, Vol. 11, (2)
Keskin, Isil; Forsgren, Elin; Lange, Dale J.; et al.
2012
Mutant superoxide dismutase-1 indistinguishable from wild-type causes ALS
Human Molecular Genetics
, Vol. 21, (16) : 3568-3574
Synofzik, Matthis; Ronchi, Dario; Keskin, Isil; et al.
Enhanced protein misfolding in patient-derived models of amyotrophic lateral sclerosis
Forsgren, Elin; Lehmann, Manuela; Weygandt Mathis, Mackenzie; et al.
Comprehensive analysis to explain reduced or increased SOD1 enzymatic activity in erythrocytes in ALS patients and their relatives
Keskin, Isil; Birve, Anna; Berdynski, Mariusz; et al.
Low oxygen tension induces misfolding and aggregation of superoxide dismutase in ALS patient-derived motor neurons
Keskin, Isil; Forsgren, Elin; Andersen, Peter M.; et al.
Visa publikationer i DiVA
Forskargrupper
Gruppmedlem
ALS-forskning Umeå
Peter Andersens labb
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